Prostaglandin reductase 3 (PTGR3)
Homo sapiens — UniProt Q8N4Q0
Data last refreshed: (UniProt release unknown)
Key facts
Prostaglandin reductase 3 (PTGR3) is a protein from Homo sapiens identified by UniProt accession Q8N4Q0, 377 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q8N4Q0; gene symbol PTGR3.
- Organism: Homo sapiens.
- Length: 377 amino acids.
- Top disease associations (Open Targets): platelet count, vascular endothelial growth factor measurement and nose morphology measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Prostaglandin reductase 3 |
|---|---|
| UniProt accession | Q8N4Q0 |
| Gene | PTGR3 |
| Organism | Homo sapiens |
| Length | 377 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- platelet count · score 0.43
- vascular endothelial growth factor measurement · score 0.30
- nose morphology measurement · score 0.30
- platelet crit · score 0.28
- lymphocyte count · score 0.15
- systolic blood pressure · score 0.09
- prostate carcinoma · score 0.06
- protein measurement · score 0.06
- serum gamma-glutamyl transferase measurement · score 0.06
- endometrial neoplasm · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4Q0-F1 | alphafold | PREDICTED | 93.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4Q0.
Amino-acid sequence (377 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PTGR3?
The strongest Open Targets associations for PTGR3 are platelet count, vascular endothelial growth factor measurement, nose morphology measurement, platelet crit and lymphocyte count.
How long is the PTGR3 protein?
The Homo sapiens PTGR3 protein (UniProt Q8N4Q0) is 377 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4Q0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4Q0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.