Progestin and adipoQ receptor family member 4 (PAQR4)
Homo sapiens — UniProt Q8N4S7
Data last refreshed: (UniProt release unknown)
Key facts
Progestin and adipoQ receptor family member 4 (PAQR4) is a protein from Homo sapiens identified by UniProt accession Q8N4S7, 273 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8N4S7; gene symbol PAQR4.
- Organism: Homo sapiens.
- Length: 273 amino acids.
- Top disease associations (Open Targets): balding measurement, neoplasm and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Progestin and adipoQ receptor family member 4 |
|---|---|
| UniProt accession | Q8N4S7 |
| Gene | PAQR4 |
| Organism | Homo sapiens |
| Length | 273 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- balding measurement · score 0.12
- neoplasm · score 0.10
- non-small cell lung carcinoma · score 0.09
- cancer · score 0.08
- hepatocellular carcinoma · score 0.08
- uterine leiomyosarcoma · score 0.02
- bladder transitional cell carcinoma · score 0.02
- urinary bladder carcinoma · score 0.02
- colorectal cancer · score 0.02
- gonorrhea · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4S7-F1 | alphafold | PREDICTED | 94.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4S7.
Amino-acid sequence (273 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAQR4?
The strongest Open Targets associations for PAQR4 are balding measurement, neoplasm, non-small cell lung carcinoma, cancer and hepatocellular carcinoma.
How long is the PAQR4 protein?
The Homo sapiens PAQR4 protein (UniProt Q8N4S7) is 273 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4S7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4S7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.