T-complex protein 11-like protein 2 (TCP11L2)
Homo sapiens — UniProt Q8N4U5
Data last refreshed: (UniProt release unknown)
Key facts
T-complex protein 11-like protein 2 (TCP11L2) is a protein from Homo sapiens identified by UniProt accession Q8N4U5, 519 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q8N4U5; gene symbol TCP11L2.
- Organism: Homo sapiens.
- Length: 519 amino acids.
- Top disease associations (Open Targets): body height, Abnormality of refraction and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | T-complex protein 11-like protein 2 |
|---|---|
| UniProt accession | Q8N4U5 |
| Gene | TCP11L2 |
| Organism | Homo sapiens |
| Length | 519 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- Abnormality of refraction · score 0.30
- mean platelet volume · score 0.23
- self reported educational attainment · score 0.19
- mathematical ability · score 0.12
- prurigo · score 0.07
- basophil count · score 0.06
- basophil percentage of leukocytes · score 0.05
- mean corpuscular volume · score 0.04
- adolescent idiopathic scoliosis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4U5-F1 | alphafold | PREDICTED | 80.61 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4U5.
Amino-acid sequence (519 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TCP11L2?
The strongest Open Targets associations for TCP11L2 are body height, Abnormality of refraction, mean platelet volume, self reported educational attainment and mathematical ability.
How long is the TCP11L2 protein?
The Homo sapiens TCP11L2 protein (UniProt Q8N4U5) is 519 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4U5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4U5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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