ER membrane protein complex subunit 5 (MMGT1)
Homo sapiens — UniProt Q8N4V1
Data last refreshed: (UniProt release unknown)
Key facts
ER membrane protein complex subunit 5 (MMGT1) is a protein from Homo sapiens identified by UniProt accession Q8N4V1, 131 residues long. MolForge cross-references it against 0 known binders and 6 disease associations.
- UniProt accession: Q8N4V1; gene symbol MMGT1.
- Organism: Homo sapiens.
- Length: 131 amino acids.
- Top disease associations (Open Targets): Alzheimer disease, retinal degeneration and infection.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ER membrane protein complex subunit 5 |
|---|---|
| UniProt accession | Q8N4V1 |
| Gene | MMGT1 |
| Organism | Homo sapiens |
| Length | 131 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (6)
Diseases linked to this target (Open Targets).
- Alzheimer disease · score 0.00
- retinal degeneration · score 0.00
- infection · score 0.00
- infect · score 0.00
- asthma · score 0.00
- viral disease · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4V1-F1 | alphafold | PREDICTED | 79.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4V1.
Amino-acid sequence (131 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MMGT1?
The strongest Open Targets associations for MMGT1 are Alzheimer disease, retinal degeneration, infection, infect and asthma.
How long is the MMGT1 protein?
The Homo sapiens MMGT1 protein (UniProt Q8N4V1) is 131 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4V1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4V1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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