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Zinc finger protein 808 (ZNF808)

Homo sapiens — UniProt Q8N4W9

Gene: ZNF808Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 808 (ZNF808) is a protein from Homo sapiens identified by UniProt accession Q8N4W9, 903 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

  • UniProt accession: Q8N4W9; gene symbol ZNF808.
  • Organism: Homo sapiens.
  • Length: 903 amino acids.
  • Top disease associations (Open Targets): pancreatic agenesis, neonatal diabetes mellitus and neurodegenerative disease.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 808
UniProt accessionQ8N4W9
GeneZNF808
OrganismHomo sapiens
Length903 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (9)

Diseases linked to this target (Open Targets).

  • pancreatic agenesis · score 0.42
  • neonatal diabetes mellitus · score 0.37
  • neurodegenerative disease · score 0.29
  • type 2 diabetes mellitus · score 0.26
  • diabetic nephropathy · score 0.26
  • vitamin D measurement · score 0.15
  • neoplasm · score 0.01
  • diabetes mellitus · score 0.00
  • type 1 diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N4W9-F1alphafoldPREDICTED68.55—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4W9.

Amino-acid sequence (903 residues)

MLREEAAQKR KGKESGMALP QGRLTFRDVA IEFSLAEWKF LNPAQRALYR EVMLENYRNL EAVDISSKHM MKEVLSTGQG NREVIHTGTL QRHQSYHIGD FCFQEIEKEI HNIEFQCQED ERNGHEAPTT KIKKLTGSTD QHDHRHAGNK PIKDQLGSSF YSHLPELHIF QIKGEIANQL EKSTSDASSV STSQRISCRP QIHISNNYGN NPLNSSLLPQ KQEVHMREKS FPCNESGKAF NCSSLLRKHQ IPHLGDKQYK CDVCGKLFNH KQYLACHRRC HTGEKPYKCK ECGKSFSYKS SLTCHHRLHT GVKPYKCNEC GKVFRQNSAL VIHKAIHTGE KPYKCNECGK AFNQQSHLSR HQRLHTGVKP YKCKICEKAF ACHSYLANHT RIHSGEKTYK CNECGKAFNH QSSLARHHIL HTGEKPYKCE ECDKVFSQKS TLERHKRIHT GEKPYKCKVC DTAFTCNSQL ARHRRIHTGE KTYKCNECRK TFSRRSSLLC HRRLHSGEKP YKCNQCGNTF RHRASLVYHR RLHTLEKSYK CTVCNKVFMR NSVLAVHTRI HTAKKPYKCN ECGKAFNQQS HLSRHRRLHT GEKPYKCEAC DKVFGQKSAL ESHKRIHTGE KPYRCQVCDT AFTWNSQLAR HTRIHTGEKT YKCNECGKTF SYKSSLVWHR RLHGGEKSYK CKVCDKAFVC RSYVAKHTRI HSGMKPYKCN ECSKTFSNRS SLVCHRRIHS GEKPYKCSEC SKTFSQKATL LCHRRLHSGE KPYKCNDCGN TFRHWSSLVY HRRLHTGEKS YKCTVCDKAF VRNSYLARHI RIHTAEKPYK CNECGKAFNE QSHLSRHHRI HTGEKPYKCE ACDKVFSRKS HLKRHRIIHT GEKPYKCNEC GKAFSDRSTL IHHQAIHGIG KFD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF808?

The strongest Open Targets associations for ZNF808 are pancreatic agenesis, neonatal diabetes mellitus, neurodegenerative disease, type 2 diabetes mellitus and diabetic nephropathy.

How long is the ZNF808 protein?

The Homo sapiens ZNF808 protein (UniProt Q8N4W9) is 903 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N4W9
GeneZNF808
OrganismHomo sapiens
Length903
Binders0
Diseases9
View on UniProt