Ras-related protein Rab-42 (RAB42)
Homo sapiens — UniProt Q8N4Z0
Data last refreshed: (UniProt release unknown)
Key facts
Ras-related protein Rab-42 (RAB42) is a protein from Homo sapiens identified by UniProt accession Q8N4Z0, 218 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8N4Z0; gene symbol RAB42.
- Organism: Homo sapiens.
- Length: 218 amino acids.
- Top disease associations (Open Targets): lymphocyte count, insulin like growth factor measurement and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ras-related protein Rab-42 |
|---|---|
| UniProt accession | Q8N4Z0 |
| Gene | RAB42 |
| Organism | Homo sapiens |
| Length | 218 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.10
- insulin like growth factor measurement · score 0.09
- diet measurement · score 0.03
- hemoglobin measurement · score 0.03
- central nervous system cancer · score 0.02
- glioblastoma multiforme · score 0.01
- myelodysplastic syndrome · score 0.01
- uterine leiomyosarcoma · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N4Z0-F1 | alphafold | PREDICTED | 85.31 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N4Z0.
Amino-acid sequence (218 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB42?
The strongest Open Targets associations for RAB42 are lymphocyte count, insulin like growth factor measurement, diet measurement, hemoglobin measurement and central nervous system cancer.
How long is the RAB42 protein?
The Homo sapiens RAB42 protein (UniProt Q8N4Z0) is 218 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N4Z0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N4Z0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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