Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT)
Homo sapiens — UniProt Q8N5A5
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger CCCH-type with G patch domain-containing protein (ZGPAT) is a protein from Homo sapiens identified by UniProt accession Q8N5A5, 531 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q8N5A5; gene symbol ZGPAT.
- Organism: Homo sapiens.
- Length: 531 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, platelet count and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger CCCH-type with G patch domain-containing protein |
|---|---|
| UniProt accession | Q8N5A5 |
| Gene | ZGPAT |
| Organism | Homo sapiens |
| Length | 531 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.25
- platelet count · score 0.25
- neutrophil count · score 0.25
- C-reactive protein measurement · score 0.25
- body fat percentage · score 0.25
- prostate carcinoma · score 0.24
- glomerular filtration rate · score 0.24
- aspartate aminotransferase measurement · score 0.24
- serum alanine aminotransferase measurement · score 0.24
- forced expiratory volume · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5A5-F1 | alphafold | PREDICTED | 74.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5A5.
Amino-acid sequence (531 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZGPAT?
The strongest Open Targets associations for ZGPAT are sex hormone-binding globulin measurement, platelet count, neutrophil count, C-reactive protein measurement and body fat percentage.
How long is the ZGPAT protein?
The Homo sapiens ZGPAT protein (UniProt Q8N5A5) is 531 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5A5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5A5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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