S1 RNA-binding domain-containing protein 1 (SRBD1)
Homo sapiens — UniProt Q8N5C6
Data last refreshed: (UniProt release unknown)
Key facts
S1 RNA-binding domain-containing protein 1 (SRBD1) is a protein from Homo sapiens identified by UniProt accession Q8N5C6, 995 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q8N5C6; gene symbol SRBD1.
- Organism: Homo sapiens.
- Length: 995 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and hemorrhoid.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | S1 RNA-binding domain-containing protein 1 |
|---|---|
| UniProt accession | Q8N5C6 |
| Gene | SRBD1 |
| Organism | Homo sapiens |
| Length | 995 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- body height · score 0.31
- hemorrhoid · score 0.30
- glaucoma · score 0.28
- metabolite measurement · score 0.25
- hemoglobin measurement · score 0.14
- erythrocyte count · score 0.13
- lymphocyte count · score 0.11
- heel bone mineral density · score 0.08
- platelet count · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5C6-F1 | alphafold | PREDICTED | 75.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5C6.
Amino-acid sequence (995 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SRBD1?
The strongest Open Targets associations for SRBD1 are neurodegenerative disease, body height, hemorrhoid, glaucoma and metabolite measurement.
How long is the SRBD1 protein?
The Homo sapiens SRBD1 protein (UniProt Q8N5C6) is 995 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5C6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5C6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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