Small integral membrane protein 20 (SMIM20)
Homo sapiens — UniProt Q8N5G0
Data last refreshed: (UniProt release unknown)
Key facts
Small integral membrane protein 20 (SMIM20) is a protein from Homo sapiens identified by UniProt accession Q8N5G0, 67 residues long. MolForge cross-references it against 0 known binders and 125 disease associations.
- UniProt accession: Q8N5G0; gene symbol SMIM20.
- Organism: Homo sapiens.
- Length: 67 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, total blood protein measurement and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small integral membrane protein 20 |
|---|---|
| UniProt accession | Q8N5G0 |
| Gene | SMIM20 |
| Organism | Homo sapiens |
| Length | 67 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (125)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.32
- total blood protein measurement · score 0.22
- serum albumin measurement · score 0.21
- body height · score 0.19
- triglyceride measurement · score 0.17
- self reported educational attainment · score 0.17
- high density lipoprotein cholesterol measurement · score 0.16
- alcohol drinking · score 0.11
- alcohol consumption measurement · score 0.11
- apolipoprotein A 1 measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5G0-F1 | alphafold | PREDICTED | 90.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5G0.
Amino-acid sequence (67 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SMIM20?
The strongest Open Targets associations for SMIM20 are PHF-tau measurement, total blood protein measurement, serum albumin measurement, body height and triglyceride measurement.
How long is the SMIM20 protein?
The Homo sapiens SMIM20 protein (UniProt Q8N5G0) is 67 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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