Potassium channel regulatory protein (KCNRG)
Homo sapiens — UniProt Q8N5I3
Data last refreshed: (UniProt release unknown)
Key facts
Potassium channel regulatory protein (KCNRG) is a protein from Homo sapiens identified by UniProt accession Q8N5I3, 272 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q8N5I3; gene symbol KCNRG.
- Organism: Homo sapiens.
- Length: 272 amino acids.
- Top disease associations (Open Targets): lymphocyte count, sex hormone-binding globulin measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Potassium channel regulatory protein |
|---|---|
| UniProt accession | Q8N5I3 |
| Gene | KCNRG |
| Organism | Homo sapiens |
| Length | 272 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.36
- sex hormone-binding globulin measurement · score 0.34
- body height · score 0.33
- lean body mass · score 0.32
- appendicular lean mass · score 0.32
- body weight · score 0.31
- electrocardiography · score 0.31
- body mass index · score 0.30
- fat body mass · score 0.30
- eosinophil count · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5I3-F1 | alphafold | PREDICTED | 81.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5I3.
Amino-acid sequence (272 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCNRG?
The strongest Open Targets associations for KCNRG are lymphocyte count, sex hormone-binding globulin measurement, body height, lean body mass and appendicular lean mass.
How long is the KCNRG protein?
The Homo sapiens KCNRG protein (UniProt Q8N5I3) is 272 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5I3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5I3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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