Ubiquitin carboxyl-terminal hydrolase MINDY-1 (MINDY1)
Homo sapiens — UniProt Q8N5J2
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquitin carboxyl-terminal hydrolase MINDY-1 (MINDY1) is a protein from Homo sapiens identified by UniProt accession Q8N5J2, 469 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N5J2; gene symbol MINDY1.
- Organism: Homo sapiens.
- Length: 469 amino acids.
- Top disease associations (Open Targets): sex hormone-binding globulin measurement, high density lipoprotein cholesterol measurement and HbA1c measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquitin carboxyl-terminal hydrolase MINDY-1 |
|---|---|
| UniProt accession | Q8N5J2 |
| Gene | MINDY1 |
| Organism | Homo sapiens |
| Length | 469 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.21
- high density lipoprotein cholesterol measurement · score 0.18
- HbA1c measurement · score 0.18
- serum albumin measurement · score 0.14
- schizophrenia · score 0.09
- non-melanoma skin carcinoma · score 0.08
- skin cancer · score 0.08
- attention deficit hyperactivity disorder · score 0.08
- urinary bladder carcinoma · score 0.08
- breast cancer · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5J2-F1 | alphafold | PREDICTED | 72.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5J2.
Amino-acid sequence (469 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MINDY1?
The strongest Open Targets associations for MINDY1 are sex hormone-binding globulin measurement, high density lipoprotein cholesterol measurement, HbA1c measurement, serum albumin measurement and schizophrenia.
How long is the MINDY1 protein?
The Homo sapiens MINDY1 protein (UniProt Q8N5J2) is 469 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5J2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5J2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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