Ribonuclease P protein subunit p25-like protein (RPP25L)
Homo sapiens — UniProt Q8N5L8
Data last refreshed: (UniProt release unknown)
Key facts
Ribonuclease P protein subunit p25-like protein (RPP25L) is a protein from Homo sapiens identified by UniProt accession Q8N5L8, 163 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q8N5L8; gene symbol RPP25L.
- Organism: Homo sapiens.
- Length: 163 amino acids.
- Top disease associations (Open Targets): ovarian carcinoma, breast carcinoma and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribonuclease P protein subunit p25-like protein |
|---|---|
| UniProt accession | Q8N5L8 |
| Gene | RPP25L |
| Organism | Homo sapiens |
| Length | 163 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- ovarian carcinoma · score 0.23
- breast carcinoma · score 0.15
- blood protein measurement · score 0.08
- adolescent idiopathic scoliosis · score 0.08
- aspartate aminotransferase measurement · score 0.05
- testosterone measurement · score 0.04
- hypertension · score 0.04
- metabolite measurement · score 0.03
- heel bone mineral density · score 0.02
- interleukin-11 receptor subunit alpha measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5L8-F1 | alphafold | PREDICTED | 87.84 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5L8.
Amino-acid sequence (163 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RPP25L?
The strongest Open Targets associations for RPP25L are ovarian carcinoma, breast carcinoma, blood protein measurement, adolescent idiopathic scoliosis and aspartate aminotransferase measurement.
How long is the RPP25L protein?
The Homo sapiens RPP25L protein (UniProt Q8N5L8) is 163 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5L8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5L8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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