Tetratricopeptide repeat protein 9C (TTC9C)

About Tetratricopeptide repeat protein 9C

Tetratricopeptide repeat protein 9C (TTC9C) is a protein from Homo sapiens identified by UniProt accession Q8N5M4, 171 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

Target properties

Protein name	Tetratricopeptide repeat protein 9C
UniProt accession	Q8N5M4
Gene	TTC9C
Organism	Homo sapiens
Length	171 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (10)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.25
smoking status measurement · score 0.08
urate measurement · score 0.05
lymphocyte percentage of leukocytes · score 0.03
Alzheimer disease · score 0.01
ulcerative colitis · score 0.00
postpartum depression · score 0.00
neoplasm · score 0.00
breast carcinoma · score 0.00
meningococcal infection · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N5M4-F1	alphafold	PREDICTED	92.49	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5M4.

Amino-acid sequence (171 residues)

MEKRLQEAQL YKEEGNQRYR EGKYRDAVSR YHRALLQLRG LDPSLPSPLP NLGPQGPALT PEQENILHTT QTDCYNNLAA CLLQMEPVNY ERVREYSQKV LERQPDNAKA LYRAGVAFFH LQDYDQARHY LLAAVNRQPK DANVRRYLQL TQSELSSYHR KEKQLYLGMF G

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards