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Uncharacterized protein C3orf22 (C3orf22)

Homo sapiens — UniProt Q8N5N4

Gene: C3orf22Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C3orf22 (C3orf22) is a protein from Homo sapiens identified by UniProt accession Q8N5N4, 141 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q8N5N4; gene symbol C3orf22.
  • Organism: Homo sapiens.
  • Length: 141 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, platelet count and monocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C3orf22
UniProt accessionQ8N5N4
GeneC3orf22
OrganismHomo sapiens
Length141 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.39
  • platelet count · score 0.30
  • monocyte count · score 0.28
  • pentraxin-related protein PTX3 measurement · score 0.27
  • mean platelet volume · score 0.15
  • PHF-tau measurement · score 0.11
  • pappalysin‐1 measurement · score 0.09
  • breast carcinoma · score 0.01
  • secondary progressive multiple sclerosis · score 0.00
  • meningeal tuberculosis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N5N4-F1alphafoldPREDICTED65.85—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5N4.

Amino-acid sequence (141 residues)

MDSSACKKSH QSKKWRIQAQ ENFAKKFPYR LSWLTEPDPE PLQPWEVTND SNTVQLPLQK RLVPTRSIPV RGLGAPDFTS PSGSCPAPLP APSPPPLCNL WELKLLSRRF PRQLAFLLST RHTEAACPQT SKAAGLSRGL S

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C3orf22?

The strongest Open Targets associations for C3orf22 are blood protein measurement, platelet count, monocyte count, pentraxin-related protein PTX3 measurement and mean platelet volume.

How long is the C3orf22 protein?

The Homo sapiens C3orf22 protein (UniProt Q8N5N4) is 141 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N5N4
GeneC3orf22
OrganismHomo sapiens
Length141
Binders0
Diseases10
View on UniProt