Large ribosomal subunit protein mL50 (MRPL50)
Homo sapiens — UniProt Q8N5N7
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein mL50 (MRPL50) is a protein from Homo sapiens identified by UniProt accession Q8N5N7, 158 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q8N5N7; gene symbol MRPL50.
- Organism: Homo sapiens.
- Length: 158 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, protein measurement and alkaline phosphatase measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein mL50 |
|---|---|
| UniProt accession | Q8N5N7 |
| Gene | MRPL50 |
| Organism | Homo sapiens |
| Length | 158 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- protein measurement · score 0.04
- alkaline phosphatase measurement · score 0.03
- creatinine measurement · score 0.02
- apolipoprotein A 1 measurement · score 0.02
- cystatin C measurement · score 0.02
- colorectal cancer · score 0.01
- invasive breast ductal carcinoma · score 0.00
- infection · score 0.00
- Cowden syndrome 1 · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5N7-F1 | alphafold | PREDICTED | 80.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5N7.
Amino-acid sequence (158 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL50?
The strongest Open Targets associations for MRPL50 are neurodegenerative disease, protein measurement, alkaline phosphatase measurement, creatinine measurement and apolipoprotein A 1 measurement.
How long is the MRPL50 protein?
The Homo sapiens MRPL50 protein (UniProt Q8N5N7) is 158 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5N7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5N7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.