Golgi-associated RAB2 interactor protein 5B (GARIN5B)
Homo sapiens — UniProt Q8N5Q1
Data last refreshed: (UniProt release unknown)
Key facts
Golgi-associated RAB2 interactor protein 5B (GARIN5B) is a protein from Homo sapiens identified by UniProt accession Q8N5Q1, 922 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q8N5Q1; gene symbol GARIN5B.
- Organism: Homo sapiens.
- Length: 922 amino acids.
- Top disease associations (Open Targets): osteoarthritis, hip, smoking status measurement and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi-associated RAB2 interactor protein 5B |
|---|---|
| UniProt accession | Q8N5Q1 |
| Gene | GARIN5B |
| Organism | Homo sapiens |
| Length | 922 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- osteoarthritis, hip · score 0.10
- smoking status measurement · score 0.08
- sitting height measurement · score 0.04
- vital capacity · score 0.03
- neoplasm · score 0.00
- Global developmental delay · score 0.00
- small cell lung carcinoma · score 0.00
- urinary bladder carcinoma · score 0.00
- squamous cell lung carcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5Q1-F1 | alphafold | PREDICTED | 43.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5Q1.
Amino-acid sequence (922 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GARIN5B?
The strongest Open Targets associations for GARIN5B are osteoarthritis, hip, smoking status measurement, sitting height measurement, vital capacity and neoplasm.
How long is the GARIN5B protein?
The Homo sapiens GARIN5B protein (UniProt Q8N5Q1) is 922 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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