Coiled-coil domain-containing protein 33 (CCDC33)
Homo sapiens — UniProt Q8N5R6
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 33 (CCDC33) is a protein from Homo sapiens identified by UniProt accession Q8N5R6, 958 residues long. MolForge cross-references it against 0 known binders and 76 disease associations.
- UniProt accession: Q8N5R6; gene symbol CCDC33.
- Organism: Homo sapiens.
- Length: 958 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, IGF-1 measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 33 |
|---|---|
| UniProt accession | Q8N5R6 |
| Gene | CCDC33 |
| Organism | Homo sapiens |
| Length | 958 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (76)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.27
- IGF-1 measurement · score 0.26
- brain measurement · score 0.26
- bacterial meningitis · score 0.25
- systolic blood pressure · score 0.24
- neurodegenerative disease · score 0.24
- cortical surface area measurement · score 0.23
- mean corpuscular hemoglobin · score 0.22
- blood protein measurement · score 0.16
- cystatin C measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5R6-F1 | alphafold | PREDICTED | 71.80 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5R6.
Amino-acid sequence (958 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC33?
The strongest Open Targets associations for CCDC33 are diastolic blood pressure, IGF-1 measurement, brain measurement, bacterial meningitis and systolic blood pressure.
How long is the CCDC33 protein?
The Homo sapiens CCDC33 protein (UniProt Q8N5R6) is 958 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5R6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5R6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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