Ciliary microtubule inner protein 6 (CIMIP6)
Homo sapiens — UniProt Q8N5S3
Data last refreshed: (UniProt release unknown)
Key facts
Ciliary microtubule inner protein 6 (CIMIP6) is a protein from Homo sapiens identified by UniProt accession Q8N5S3, 287 residues long. MolForge cross-references it against 0 known binders and 67 disease associations.
- UniProt accession: Q8N5S3; gene symbol CIMIP6.
- Organism: Homo sapiens.
- Length: 287 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, glomerular filtration rate and creatinine measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ciliary microtubule inner protein 6 |
|---|---|
| UniProt accession | Q8N5S3 |
| Gene | CIMIP6 |
| Organism | Homo sapiens |
| Length | 287 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (67)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.42
- glomerular filtration rate · score 0.42
- creatinine measurement · score 0.40
- cortical surface area measurement · score 0.39
- neuroimaging measurement · score 0.35
- brain measurement · score 0.33
- cortical thickness · score 0.33
- cystatin C measurement · score 0.32
- blood urea nitrogen measurement · score 0.31
- bone density · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5S3-F1 | alphafold | PREDICTED | 53.49 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5S3.
Amino-acid sequence (287 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CIMIP6?
The strongest Open Targets associations for CIMIP6 are heel bone mineral density, glomerular filtration rate, creatinine measurement, cortical surface area measurement and neuroimaging measurement.
How long is the CIMIP6 protein?
The Homo sapiens CIMIP6 protein (UniProt Q8N5S3) is 287 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5S3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5S3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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