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Uncharacterized protein C11orf42 (C11orf42)

Homo sapiens — UniProt Q8N5U0

Gene: C11orf42Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Uncharacterized protein C11orf42 (C11orf42) is a protein from Homo sapiens identified by UniProt accession Q8N5U0, 333 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

  • UniProt accession: Q8N5U0; gene symbol C11orf42.
  • Organism: Homo sapiens.
  • Length: 333 amino acids.
  • Top disease associations (Open Targets): Thalassemia, neurodegenerative disease and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUncharacterized protein C11orf42
UniProt accessionQ8N5U0
GeneC11orf42
OrganismHomo sapiens
Length333 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (15)

Diseases linked to this target (Open Targets).

  • Thalassemia · score 0.41
  • neurodegenerative disease · score 0.29
  • body mass index · score 0.04
  • mathematical ability · score 0.03
  • gastroesophageal reflux disease · score 0.03
  • duodenal ulcer · score 0.02
  • mean corpuscular volume · score 0.02
  • mean corpuscular hemoglobin · score 0.02
  • glioblastoma multiforme · score 0.01
  • cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N5U0-F1alphafoldPREDICTED71.14—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5U0.

Amino-acid sequence (333 residues)

MLVGTPNLLT LDEADATWTL IKDKVIEEHF GPNAVAVPFL SDAACYDLLG VLVKQSRPAH TRLALPGRQG RRALKPVGPL PSLLEQAGSE GAFAHCTREY SPNGRAERAY EETRMLDGQP CKIRLHMGDL RKKVAFLLLP PGQVSLQQTL PWLRSTHSIY VIYQVFSCSW LQLGLTSTAR EPQLLRLLRS LPVAFSCLKF SLQSKGVLGP QKPLTKDPLP HGANWVRPNL SIMPPLAPTS APADTTEAAD VPPPVPAPPT PPPQEGPEDK PTRFSYKGRN PFWRGPQILS ENWLFSPRSP PPGAQGGGPR DPDGHSMSLP LLQGLSSEFD SDD

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C11orf42?

The strongest Open Targets associations for C11orf42 are Thalassemia, neurodegenerative disease, body mass index, mathematical ability and gastroesophageal reflux disease.

How long is the C11orf42 protein?

The Homo sapiens C11orf42 protein (UniProt Q8N5U0) is 333 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N5U0
GeneC11orf42
OrganismHomo sapiens
Length333
Binders0
Diseases15
View on UniProt