Membrane-spanning 4-domains subfamily A member 15 (MS4A15)
Homo sapiens — UniProt Q8N5U1
Data last refreshed: (UniProt release unknown)
Key facts
Membrane-spanning 4-domains subfamily A member 15 (MS4A15) is a protein from Homo sapiens identified by UniProt accession Q8N5U1, 240 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q8N5U1; gene symbol MS4A15.
- Organism: Homo sapiens.
- Length: 240 amino acids.
- Top disease associations (Open Targets): sleep apnea measurement, breast carcinoma and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Membrane-spanning 4-domains subfamily A member 15 |
|---|---|
| UniProt accession | Q8N5U1 |
| Gene | MS4A15 |
| Organism | Homo sapiens |
| Length | 240 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- sleep apnea measurement · score 0.25
- breast carcinoma · score 0.04
- non-small cell lung carcinoma · score 0.03
- eosinophil count · score 0.02
- neurofibrillary tangles measurement · score 0.02
- lung adenocarcinoma · score 0.02
- COVID-19 · score 0.02
- gastric cancer · score 0.02
- lung carcinoma · score 0.02
- colorectal adenocarcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5U1-F1 | alphafold | PREDICTED | 68.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5U1.
Amino-acid sequence (240 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MS4A15?
The strongest Open Targets associations for MS4A15 are sleep apnea measurement, breast carcinoma, non-small cell lung carcinoma, eosinophil count and neurofibrillary tangles measurement.
How long is the MS4A15 protein?
The Homo sapiens MS4A15 protein (UniProt Q8N5U1) is 240 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5U1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5U1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.