MSL complex subunit 3 (MSL3)
Homo sapiens — UniProt Q8N5Y2
Data last refreshed: (UniProt release unknown)
Key facts
MSL complex subunit 3 (MSL3) is a protein from Homo sapiens identified by UniProt accession Q8N5Y2, 521 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.
- UniProt accession: Q8N5Y2; gene symbol MSL3.
- Organism: Homo sapiens.
- Length: 521 amino acids.
- Top disease associations (Open Targets): Basilicata-Akhtar syndrome, genetic disorder and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MSL complex subunit 3 |
|---|---|
| UniProt accession | Q8N5Y2 |
| Gene | MSL3 |
| Organism | Homo sapiens |
| Length | 521 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (36)
Diseases linked to this target (Open Targets).
- Basilicata-Akhtar syndrome · score 0.76
- genetic disorder · score 0.50
- Intellectual disability · score 0.50
- neurodegenerative disease · score 0.43
- Feeding difficulties · score 0.37
- Neurodevelopmental delay · score 0.37
- Hypotonia · score 0.37
- Global developmental delay · score 0.34
- Neurodevelopmental abnormality · score 0.33
- breast adenocarcinoma · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5Y2-F1 | alphafold | PREDICTED | 68.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5Y2.
Amino-acid sequence (521 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MSL3?
The strongest Open Targets associations for MSL3 are Basilicata-Akhtar syndrome, genetic disorder, Intellectual disability, neurodegenerative disease and Feeding difficulties.
How long is the MSL3 protein?
The Homo sapiens MSL3 protein (UniProt Q8N5Y2) is 521 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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