BTB/POZ domain-containing protein KCTD17 (KCTD17)
Homo sapiens — UniProt Q8N5Z5
Data last refreshed: (UniProt release unknown)
Key facts
BTB/POZ domain-containing protein KCTD17 (KCTD17) is a protein from Homo sapiens identified by UniProt accession Q8N5Z5, 314 residues long. MolForge cross-references it against 0 known binders and 58 disease associations.
- UniProt accession: Q8N5Z5; gene symbol KCTD17.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Top disease associations (Open Targets): myoclonic dystonia 26, myoclonus-dystonia syndrome and mean corpuscular volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BTB/POZ domain-containing protein KCTD17 |
|---|---|
| UniProt accession | Q8N5Z5 |
| Gene | KCTD17 |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (58)
Diseases linked to this target (Open Targets).
- myoclonic dystonia 26 · score 0.59
- myoclonus-dystonia syndrome · score 0.37
- mean corpuscular volume · score 0.32
- mean corpuscular hemoglobin · score 0.28
- Red cell distribution width · score 0.20
- genetic disorder · score 0.19
- bilirubin measurement · score 0.19
- mean corpuscular hemoglobin concentration · score 0.15
- HbA1c measurement · score 0.15
- hemoglobin measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N5Z5-F1 | alphafold | PREDICTED | 70.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N5Z5.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KCTD17?
The strongest Open Targets associations for KCTD17 are myoclonic dystonia 26, myoclonus-dystonia syndrome, mean corpuscular volume, mean corpuscular hemoglobin and Red cell distribution width.
How long is the KCTD17 protein?
The Homo sapiens KCTD17 protein (UniProt Q8N5Z5) is 314 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N5Z5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N5Z5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.