FHF complex subunit HOOK-interacting protein 1B (FHIP1B)
Homo sapiens — UniProt Q8N612
Data last refreshed: (UniProt release unknown)
Key facts
FHF complex subunit HOOK-interacting protein 1B (FHIP1B) is a protein from Homo sapiens identified by UniProt accession Q8N612, 972 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q8N612; gene symbol FHIP1B.
- Organism: Homo sapiens.
- Length: 972 amino acids.
- Top disease associations (Open Targets): body mass index, prostate carcinoma and prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FHF complex subunit HOOK-interacting protein 1B |
|---|---|
| UniProt accession | Q8N612 |
| Gene | FHIP1B |
| Organism | Homo sapiens |
| Length | 972 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- body mass index · score 0.21
- prostate carcinoma · score 0.11
- prostate cancer · score 0.11
- Familial prostate cancer · score 0.11
- duodenal ulcer · score 0.09
- mean corpuscular volume · score 0.08
- mean corpuscular hemoglobin · score 0.08
- mathematical ability · score 0.06
- gastroesophageal reflux disease · score 0.05
- peptic ulcer disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N612-F1 | alphafold | PREDICTED | 68.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N612.
Amino-acid sequence (972 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FHIP1B?
The strongest Open Targets associations for FHIP1B are body mass index, prostate carcinoma, prostate cancer, Familial prostate cancer and duodenal ulcer.
How long is the FHIP1B protein?
The Homo sapiens FHIP1B protein (UniProt Q8N612) is 972 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N612 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N612 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.