Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3)
Homo sapiens — UniProt Q8N6C8
Data last refreshed: (UniProt release unknown)
Key facts
Leukocyte immunoglobulin-like receptor subfamily A member 3 (LILRA3) is a protein from Homo sapiens identified by UniProt accession Q8N6C8, 439 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q8N6C8; gene symbol LILRA3.
- Organism: Homo sapiens.
- Length: 439 amino acids.
- Top disease associations (Open Targets): myeloid sarcoma, adult-onset Still's disease and inflammatory bowel disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leukocyte immunoglobulin-like receptor subfamily A member 3 |
|---|---|
| UniProt accession | Q8N6C8 |
| Gene | LILRA3 |
| Organism | Homo sapiens |
| Length | 439 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- myeloid sarcoma · score 0.08
- adult-onset Still's disease · score 0.08
- inflammatory bowel disease · score 0.06
- Systemic lupus erythematosus · score 0.05
- Rheumatoid arthritis · score 0.05
- ulcerative colitis · score 0.03
- multiple sclerosis · score 0.03
- HIV infection · score 0.03
- alkaline phosphatase measurement · score 0.02
- Sjogren syndrome · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6C8-F1 | alphafold | PREDICTED | 87.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6C8.
Amino-acid sequence (439 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LILRA3?
The strongest Open Targets associations for LILRA3 are myeloid sarcoma, adult-onset Still's disease, inflammatory bowel disease, Systemic lupus erythematosus and Rheumatoid arthritis.
How long is the LILRA3 protein?
The Homo sapiens LILRA3 protein (UniProt Q8N6C8) is 439 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6C8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6C8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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