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Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2)

Homo sapiens — UniProt Q8N6G5

Gene: CSGALNACT2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) is a protein from Homo sapiens identified by UniProt accession Q8N6G5, 542 residues long. MolForge cross-references it against 0 known binders and 46 disease associations.

  • UniProt accession: Q8N6G5; gene symbol CSGALNACT2.
  • Organism: Homo sapiens.
  • Length: 542 amino acids.
  • Top disease associations (Open Targets): blood protein measurement, cortical surface area measurement and body height.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameChondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt accessionQ8N6G5
GeneCSGALNACT2
OrganismHomo sapiens
Length542 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (46)

Diseases linked to this target (Open Targets).

  • blood protein measurement · score 0.33
  • cortical surface area measurement · score 0.28
  • body height · score 0.25
  • BMI-adjusted hip circumference · score 0.25
  • cigarettes per day measurement · score 0.24
  • central corneal thickness · score 0.24
  • Hirschsprung disease · score 0.20
  • appendicular lean mass · score 0.17
  • brain measurement · score 0.16
  • total blood protein measurement · score 0.14

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N6G5-F1alphafoldPREDICTED86.63—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6G5.

Amino-acid sequence (542 residues)

MPRRGLILHT RTHWLLLGLA LLCSLVLFMY LLECAPQTDG NASLPGVVGE NYGKEYYQAL LQEQEEHYQT RATSLKRQIA QLKQELQEMS EKMRSLQERR NVGANGIGYQ SNKEQAPSDL LEFLHSQIDK AEVSIGAKLP SEYGVIPFES FTLMKVFQLE MGLTRHPEEK PVRKDKRDEL VEVIEAGLEV INNPDEDDEQ EDEEGPLGEK LIFNENDFVE GYYRTERDKG TQYELFFKKA DLTEYRHVTL FRPFGPLMKV KSEMIDITRS IINIIVPLAE RTEAFVQFMQ NFRDVCIHQD KKIHLTVVYF GKEGLSKVKS ILESVTSESN FHNYTLVSLN EEFNRGRGLN VGARAWDKGE VLMFFCDVDI YFSAEFLNSC RLNAEPGKKV FYPVVFSLYN PAIVYANQEV PPPVEQQLVH KKDSGFWRDF GFGMTCQYRS DFLTIGGFDM EVKGWGGEDV HLYRKYLHGD LIVIRTPVPG LFHLWHEKRC ADELTPEQYR MCIQSKAMNE ASHSHLGMLV FREEIETHLH KQAYRTNSEA VG

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CSGALNACT2?

The strongest Open Targets associations for CSGALNACT2 are blood protein measurement, cortical surface area measurement, body height, BMI-adjusted hip circumference and cigarettes per day measurement.

How long is the CSGALNACT2 protein?

The Homo sapiens CSGALNACT2 protein (UniProt Q8N6G5) is 542 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N6G5
GeneCSGALNACT2
OrganismHomo sapiens
Length542
Binders0
Diseases46
View on UniProt