EP300-interacting inhibitor of differentiation 2 (EID2)
Homo sapiens — UniProt Q8N6I1
Data last refreshed: (UniProt release unknown)
Key facts
EP300-interacting inhibitor of differentiation 2 (EID2) is a protein from Homo sapiens identified by UniProt accession Q8N6I1, 236 residues long. MolForge cross-references it against 0 known binders and 51 disease associations.
- UniProt accession: Q8N6I1; gene symbol EID2.
- Organism: Homo sapiens.
- Length: 236 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, attention deficit hyperactivity disorder and attention deficit-hyperactivity disorder 8.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | EP300-interacting inhibitor of differentiation 2 |
|---|---|
| UniProt accession | Q8N6I1 |
| Gene | EID2 |
| Organism | Homo sapiens |
| Length | 236 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (51)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.23
- attention deficit hyperactivity disorder · score 0.07
- attention deficit-hyperactivity disorder 8 · score 0.05
- schizophrenia 15 · score 0.05
- Tourette syndrome · score 0.05
- Cataract-microcornea syndrome · score 0.05
- autism · score 0.05
- Phelan-McDermid syndrome · score 0.05
- early-onset non-syndromic cataract · score 0.05
- Cataract with Y-shaped suture opacities · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6I1-F1 | alphafold | PREDICTED | 56.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6I1.
Amino-acid sequence (236 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EID2?
The strongest Open Targets associations for EID2 are neurodegenerative disease, attention deficit hyperactivity disorder, attention deficit-hyperactivity disorder 8, schizophrenia 15 and Tourette syndrome.
How long is the EID2 protein?
The Homo sapiens EID2 protein (UniProt Q8N6I1) is 236 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6I1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6I1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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