Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2 (KRTCAP2)
Homo sapiens — UniProt Q8N6L1
Data last refreshed: (UniProt release unknown)
Key facts
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2 (KRTCAP2) is a protein from Homo sapiens identified by UniProt accession Q8N6L1, 136 residues long. MolForge cross-references it against 0 known binders and 74 disease associations.
- UniProt accession: Q8N6L1; gene symbol KRTCAP2.
- Organism: Homo sapiens.
- Length: 136 amino acids.
- Top disease associations (Open Targets): PR interval, neuroimaging measurement and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2 |
|---|---|
| UniProt accession | Q8N6L1 |
| Gene | KRTCAP2 |
| Organism | Homo sapiens |
| Length | 136 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (74)
Diseases linked to this target (Open Targets).
- PR interval · score 0.24
- neuroimaging measurement · score 0.20
- appendicular lean mass · score 0.20
- brain volume measurement · score 0.19
- brain measurement · score 0.18
- acute myeloid leukemia · score 0.17
- body fat distribution · score 0.16
- magnesium measurement · score 0.15
- allergic disease · score 0.14
- breast carcinoma · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6L1-F1 | alphafold | PREDICTED | 82.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6L1.
Amino-acid sequence (136 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTCAP2?
The strongest Open Targets associations for KRTCAP2 are PR interval, neuroimaging measurement, appendicular lean mass, brain volume measurement and brain measurement.
How long is the KRTCAP2 protein?
The Homo sapiens KRTCAP2 protein (UniProt Q8N6L1) is 136 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6L1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6L1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.