Aminopeptidase O (AOPEP)
Homo sapiens — UniProt Q8N6M6
Data last refreshed: (UniProt release unknown)
Key facts
Aminopeptidase O (AOPEP) is a protein from Homo sapiens identified by UniProt accession Q8N6M6, 819 residues long. MolForge cross-references it against 0 known binders and 1,118 disease associations.
- UniProt accession: Q8N6M6; gene symbol AOPEP.
- Organism: Homo sapiens.
- Length: 819 amino acids.
- Top disease associations (Open Targets): atrial fibrillation, calcium measurement and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Aminopeptidase O |
|---|---|
| UniProt accession | Q8N6M6 |
| Gene | AOPEP |
| Organism | Homo sapiens |
| Length | 819 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (1118)
Diseases linked to this target (Open Targets).
- atrial fibrillation · score 0.51
- calcium measurement · score 0.46
- body height · score 0.44
- polycystic ovary syndrome · score 0.44
- appendicular lean mass · score 0.42
- snoring measurement · score 0.41
- type 2 diabetes mellitus · score 0.36
- IGF-1 measurement · score 0.34
- fat body mass · score 0.31
- lean body mass · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6M6-F1 | alphafold | PREDICTED | 82.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6M6.
Amino-acid sequence (819 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AOPEP?
The strongest Open Targets associations for AOPEP are atrial fibrillation, calcium measurement, body height, polycystic ovary syndrome and appendicular lean mass.
How long is the AOPEP protein?
The Homo sapiens AOPEP protein (UniProt Q8N6M6) is 819 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6M6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6M6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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