IQ domain-containing protein F1 (IQCF1)
Homo sapiens — UniProt Q8N6M8
Data last refreshed: (UniProt release unknown)
Key facts
IQ domain-containing protein F1 (IQCF1) is a protein from Homo sapiens identified by UniProt accession Q8N6M8, 205 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N6M8; gene symbol IQCF1.
- Organism: Homo sapiens.
- Length: 205 amino acids.
- Top disease associations (Open Targets): apolipoprotein A 1 measurement, high density lipoprotein cholesterol measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | IQ domain-containing protein F1 |
|---|---|
| UniProt accession | Q8N6M8 |
| Gene | IQCF1 |
| Organism | Homo sapiens |
| Length | 205 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- apolipoprotein A 1 measurement · score 0.16
- high density lipoprotein cholesterol measurement · score 0.16
- body mass index · score 0.13
- MODY · score 0.11
- type 2 diabetes mellitus · score 0.08
- azoospermia · score 0.07
- type 1 diabetes mellitus · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- diabetes mellitus, transient neonatal, 2 · score 0.07
- spermatogenic failure 3 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6M8-F1 | alphafold | PREDICTED | 76.56 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6M8.
Amino-acid sequence (205 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IQCF1?
The strongest Open Targets associations for IQCF1 are apolipoprotein A 1 measurement, high density lipoprotein cholesterol measurement, body mass index, MODY and type 2 diabetes mellitus.
How long is the IQCF1 protein?
The Homo sapiens IQCF1 protein (UniProt Q8N6M8) is 205 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6M8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6M8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.