AN1-type zinc finger protein 2A (ZFAND2A)
Homo sapiens — UniProt Q8N6M9
Data last refreshed: (UniProt release unknown)
Key facts
AN1-type zinc finger protein 2A (ZFAND2A) is a protein from Homo sapiens identified by UniProt accession Q8N6M9, 145 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N6M9; gene symbol ZFAND2A.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, systolic blood pressure and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | AN1-type zinc finger protein 2A |
|---|---|
| UniProt accession | Q8N6M9 |
| Gene | ZFAND2A |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.33
- systolic blood pressure · score 0.33
- hypertension · score 0.21
- apolipoprotein A 1 measurement · score 0.17
- mean corpuscular volume · score 0.17
- cardiovascular disease · score 0.15
- Agents acting on the renin-angiotensin system use measurement · score 0.15
- aspartate aminotransferase measurement · score 0.13
- reticulocyte measurement · score 0.13
- high density lipoprotein cholesterol measurement · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6M9-F1 | alphafold | PREDICTED | 85.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6M9.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZFAND2A?
The strongest Open Targets associations for ZFAND2A are diastolic blood pressure, systolic blood pressure, hypertension, apolipoprotein A 1 measurement and mean corpuscular volume.
How long is the ZFAND2A protein?
The Homo sapiens ZFAND2A protein (UniProt Q8N6M9) is 145 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6M9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6M9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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