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UPF0690 protein C1orf52 (C1orf52)

Homo sapiens — UniProt Q8N6N3

Gene: C1orf52Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

UPF0690 protein C1orf52 (C1orf52) is a protein from Homo sapiens identified by UniProt accession Q8N6N3, 182 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

  • UniProt accession: Q8N6N3; gene symbol C1orf52.
  • Organism: Homo sapiens.
  • Length: 182 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, protein measurement and urinary metabolite measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameUPF0690 protein C1orf52
UniProt accessionQ8N6N3
GeneC1orf52
OrganismHomo sapiens
Length182 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (20)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.21
  • protein measurement · score 0.04
  • urinary metabolite measurement · score 0.04
  • NG-monomethyl-arginine measurement · score 0.04
  • cortical surface area measurement · score 0.04
  • body mass index · score 0.04
  • lean body mass · score 0.04
  • multiple sclerosis · score 0.03
  • serum dimethylarginine measurement · score 0.03
  • serum metabolite measurement · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N6N3-F1alphafoldPREDICTED61.69—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6N3.

Amino-acid sequence (182 residues)

MAAEEKDPLS YFAAYGSSSS GSSDEEDNIE PEETSRRTPD PAKSAGGCRN KAEKRLPGPD ELFRSVTRPA FLYNPLNKQI DWERHVVKAP EEPPKEFKIW KSNYVPPPET YTTEKKPPPP ELDMAIKWSN IYEDNGDDAP QNAKKARLLP EGEETLESDD EKDEHTSKKR KVEPGEPAKK KK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with C1orf52?

The strongest Open Targets associations for C1orf52 are neurodegenerative disease, protein measurement, urinary metabolite measurement, NG-monomethyl-arginine measurement and cortical surface area measurement.

How long is the C1orf52 protein?

The Homo sapiens C1orf52 protein (UniProt Q8N6N3) is 182 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N6N3
GeneC1orf52
OrganismHomo sapiens
Length182
Binders0
Diseases20
View on UniProt