Ankyrin repeat domain-containing protein 13C (ANKRD13C)
Homo sapiens — UniProt Q8N6S4
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat domain-containing protein 13C (ANKRD13C) is a protein from Homo sapiens identified by UniProt accession Q8N6S4, 541 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.
- UniProt accession: Q8N6S4; gene symbol ANKRD13C.
- Organism: Homo sapiens.
- Length: 541 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, colorectal cancer and colon carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat domain-containing protein 13C |
|---|---|
| UniProt accession | Q8N6S4 |
| Gene | ANKRD13C |
| Organism | Homo sapiens |
| Length | 541 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (32)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.35
- colorectal cancer · score 0.11
- colon carcinoma · score 0.11
- inflammatory bowel disease · score 0.06
- hemoglobin D disease · score 0.05
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome · score 0.05
- dominant beta-thalassemia · score 0.04
- Familial exudative vitreoretinopathy · score 0.04
- hemoglobin H disease · score 0.04
- hemoglobin E disease · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6S4-F1 | alphafold | PREDICTED | 74.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6S4.
Amino-acid sequence (541 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANKRD13C?
The strongest Open Targets associations for ANKRD13C are neurodegenerative disease, colorectal cancer, colon carcinoma, inflammatory bowel disease and hemoglobin D disease.
How long is the ANKRD13C protein?
The Homo sapiens ANKRD13C protein (UniProt Q8N6S4) is 541 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6S4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6S4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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