ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6)
Homo sapiens — UniProt Q8N6S5
Data last refreshed: (UniProt release unknown)
Key facts
ADP-ribosylation factor-like protein 6-interacting protein 6 (ARL6IP6) is a protein from Homo sapiens identified by UniProt accession Q8N6S5, 226 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q8N6S5; gene symbol ARL6IP6.
- Organism: Homo sapiens.
- Length: 226 amino acids.
- Top disease associations (Open Targets): Bardet-Biedl syndrome, pulse pressure measurement and puberty onset measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ADP-ribosylation factor-like protein 6-interacting protein 6 |
|---|---|
| UniProt accession | Q8N6S5 |
| Gene | ARL6IP6 |
| Organism | Homo sapiens |
| Length | 226 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- Bardet-Biedl syndrome · score 0.27
- pulse pressure measurement · score 0.22
- puberty onset measurement · score 0.19
- adolescent idiopathic scoliosis · score 0.18
- Abnormality of refraction · score 0.17
- heel bone mineral density · score 0.14
- gut microbiome measurement · score 0.14
- bone quantitative ultrasound measurement · score 0.12
- bone density · score 0.12
- age at menarche · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6S5-F1 | alphafold | PREDICTED | 56.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6S5.
Amino-acid sequence (226 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARL6IP6?
The strongest Open Targets associations for ARL6IP6 are Bardet-Biedl syndrome, pulse pressure measurement, puberty onset measurement, adolescent idiopathic scoliosis and Abnormality of refraction.
How long is the ARL6IP6 protein?
The Homo sapiens ARL6IP6 protein (UniProt Q8N6S5) is 226 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6S5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6S5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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