UPF0728 protein C10orf53 (C10orf53)
Homo sapiens — UniProt Q8N6V4
Data last refreshed: (UniProt release unknown)
Key facts
UPF0728 protein C10orf53 (C10orf53) is a protein from Homo sapiens identified by UniProt accession Q8N6V4, 93 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q8N6V4; gene symbol C10orf53.
- Organism: Homo sapiens.
- Length: 93 amino acids.
- Top disease associations (Open Targets): primary angle closure glaucoma, PHF-tau measurement and hematocrit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UPF0728 protein C10orf53 |
|---|---|
| UniProt accession | Q8N6V4 |
| Gene | C10orf53 |
| Organism | Homo sapiens |
| Length | 93 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- primary angle closure glaucoma · score 0.31
- PHF-tau measurement · score 0.08
- hematocrit · score 0.03
- breast carcinoma · score 0.01
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6V4-F1 | alphafold | PREDICTED | 93.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6V4.
Amino-acid sequence (93 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C10orf53?
The strongest Open Targets associations for C10orf53 are primary angle closure glaucoma, PHF-tau measurement, hematocrit, breast carcinoma and acute myeloid leukemia.
How long is the C10orf53 protein?
The Homo sapiens C10orf53 protein (UniProt Q8N6V4) is 93 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6V4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6V4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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