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CUGBP Elav-like family member 5 (CELF5)

Homo sapiens — UniProt Q8N6W0

Gene: CELF5Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

CUGBP Elav-like family member 5 (CELF5) is a protein from Homo sapiens identified by UniProt accession Q8N6W0, 485 residues long. MolForge cross-references it against 0 known binders and 36 disease associations.

  • UniProt accession: Q8N6W0; gene symbol CELF5.
  • Organism: Homo sapiens.
  • Length: 485 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and leukocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCUGBP Elav-like family member 5
UniProt accessionQ8N6W0
GeneCELF5
OrganismHomo sapiens
Length485 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (36)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.52
  • self reported educational attainment · score 0.36
  • leukocyte count · score 0.35
  • lysosomal storage disease · score 0.34
  • brain measurement · score 0.24
  • cortical surface area measurement · score 0.22
  • cortical thickness · score 0.21
  • neutrophil count · score 0.10
  • body height · score 0.08
  • monocyte count · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N6W0-F1alphafoldPREDICTED67.76—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6W0.

Amino-acid sequence (485 residues)

MARLTESEAR RQQQQLLQPR PSPVGSSGPE PPGGQPDGMK DLDAIKLFVG QIPRHLDEKD LKPLFEQFGR IYELTVLKDP YTGMHKGCAF LTYCARDSAI KAQTALHEQK TLPGMARPIQ VKPADSESRG GRDRKLFVGM LNKQQSEEDV LRLFQPFGVI DECTVLRGPD GSSKGCAFVK FSSHTEAQAA IHALHGSQTM PGASSSLVVK FADTDKERTL RRMQQMVGQL GILTPSLTLP FSPYSAYAQA LMQQQTTVLS TSGSYLSPGV AFSPCHIQQI GAVSLNGLPA TPIAPASGLH SPPLLGTTAV PGLVAPITNG FAGVVPFPGG HPALETVYAN GLVPYPAQSP TVAETLHPAF SGVQQYTAMY PTAAITPIAH SVPQPPPLLQ QQQREGPEGC NLFIYHLPQE FGDTELTQMF LPFGNIISSK VFMDRATNQS KCFGFVSFDN PASAQAAIQA MNGFQIGMKR LKVQLKRPKD PGHPY

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CELF5?

The strongest Open Targets associations for CELF5 are neurodegenerative disease, self reported educational attainment, leukocyte count, lysosomal storage disease and brain measurement.

How long is the CELF5 protein?

The Homo sapiens CELF5 protein (UniProt Q8N6W0) is 485 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N6W0
GeneCELF5
OrganismHomo sapiens
Length485
Binders0
Diseases36
View on UniProt