Harmonin-binding protein USHBP1 (USHBP1)
Homo sapiens — UniProt Q8N6Y0
Data last refreshed: (UniProt release unknown)
Key facts
Harmonin-binding protein USHBP1 (USHBP1) is a protein from Homo sapiens identified by UniProt accession Q8N6Y0, 703 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.
- UniProt accession: Q8N6Y0; gene symbol USHBP1.
- Organism: Homo sapiens.
- Length: 703 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, mitochondrial DNA measurement and breast carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Harmonin-binding protein USHBP1 |
|---|---|
| UniProt accession | Q8N6Y0 |
| Gene | USHBP1 |
| Organism | Homo sapiens |
| Length | 703 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (49)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.25
- mitochondrial DNA measurement · score 0.23
- breast carcinoma · score 0.16
- ovarian serous carcinoma · score 0.15
- ovarian carcinoma · score 0.15
- estrogen-receptor negative breast cancer · score 0.15
- prostate carcinoma · score 0.10
- lung adenocarcinoma · score 0.10
- squamous cell lung carcinoma · score 0.10
- lung carcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6Y0-F1 | alphafold | PREDICTED | 68.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6Y0.
Amino-acid sequence (703 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with USHBP1?
The strongest Open Targets associations for USHBP1 are diastolic blood pressure, mitochondrial DNA measurement, breast carcinoma, ovarian serous carcinoma and ovarian carcinoma.
How long is the USHBP1 protein?
The Homo sapiens USHBP1 protein (UniProt Q8N6Y0) is 703 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6Y0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6Y0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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