Protocadherin-20 (PCDH20)
Homo sapiens — UniProt Q8N6Y1
Data last refreshed: (UniProt release unknown)
Key facts
Protocadherin-20 (PCDH20) is a protein from Homo sapiens identified by UniProt accession Q8N6Y1, 951 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q8N6Y1; gene symbol PCDH20.
- Organism: Homo sapiens.
- Length: 951 amino acids.
- Top disease associations (Open Targets): age at menarche, insomnia measurement and adolescent idiopathic scoliosis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protocadherin-20 |
|---|---|
| UniProt accession | Q8N6Y1 |
| Gene | PCDH20 |
| Organism | Homo sapiens |
| Length | 951 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- age at menarche · score 0.23
- insomnia measurement · score 0.21
- adolescent idiopathic scoliosis · score 0.18
- drug use measurement · score 0.14
- hepatocellular carcinoma · score 0.09
- neoplasm · score 0.08
- colitis · score 0.07
- esophageal squamous cell carcinoma · score 0.07
- Asperger syndrome · score 0.07
- autism · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N6Y1-F1 | alphafold | PREDICTED | 78.08 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N6Y1.
Amino-acid sequence (951 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PCDH20?
The strongest Open Targets associations for PCDH20 are age at menarche, insomnia measurement, adolescent idiopathic scoliosis, drug use measurement and hepatocellular carcinoma.
How long is the PCDH20 protein?
The Homo sapiens PCDH20 protein (UniProt Q8N6Y1) is 951 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N6Y1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N6Y1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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