Coiled-coil domain-containing protein 185 (CCDC185)
Homo sapiens — UniProt Q8N715
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 185 (CCDC185) is a protein from Homo sapiens identified by UniProt accession Q8N715, 623 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q8N715; gene symbol CCDC185.
- Organism: Homo sapiens.
- Length: 623 amino acids.
- Top disease associations (Open Targets): PHF-tau measurement, metabolite measurement and glucuronate measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 185 |
|---|---|
| UniProt accession | Q8N715 |
| Gene | CCDC185 |
| Organism | Homo sapiens |
| Length | 623 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- PHF-tau measurement · score 0.23
- metabolite measurement · score 0.05
- glucuronate measurement · score 0.03
- excessive daytime sleepiness measurement · score 0.02
- heel bone mineral density · score 0.02
- non-small cell lung carcinoma · score 0.02
- complete androgen insensitivity syndrome · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N715-F1 | alphafold | PREDICTED | 68.27 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N715.
Amino-acid sequence (623 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC185?
The strongest Open Targets associations for CCDC185 are PHF-tau measurement, metabolite measurement, glucuronate measurement, excessive daytime sleepiness measurement and heel bone mineral density.
How long is the CCDC185 protein?
The Homo sapiens CCDC185 protein (UniProt Q8N715) is 623 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N715 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N715 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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