PACRG-like protein (PACRGL)
Homo sapiens — UniProt Q8N7B6
Data last refreshed: (UniProt release unknown)
Key facts
PACRG-like protein (PACRGL) is a protein from Homo sapiens identified by UniProt accession Q8N7B6, 248 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.
- UniProt accession: Q8N7B6; gene symbol PACRGL.
- Organism: Homo sapiens.
- Length: 248 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, Abnormality of the digestive system and body fat percentage.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PACRG-like protein |
|---|---|
| UniProt accession | Q8N7B6 |
| Gene | PACRGL |
| Organism | Homo sapiens |
| Length | 248 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (20)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.20
- Abnormality of the digestive system · score 0.09
- body fat percentage · score 0.08
- diffuse plaque measurement · score 0.07
- body mass index · score 0.06
- lean body mass · score 0.06
- attention deficit hyperactivity disorder · score 0.05
- antisocial behaviour measurement · score 0.05
- substance abuse · score 0.05
- adolescent idiopathic scoliosis · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7B6-F1 | alphafold | PREDICTED | 78.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7B6.
Amino-acid sequence (248 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PACRGL?
The strongest Open Targets associations for PACRGL are serum metabolite measurement, Abnormality of the digestive system, body fat percentage, diffuse plaque measurement and body mass index.
How long is the PACRGL protein?
The Homo sapiens PACRGL protein (UniProt Q8N7B6) is 248 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7B6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7B6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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