Zinc finger protein 433 (ZNF433)
Homo sapiens — UniProt Q8N7K0
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 433 (ZNF433) is a protein from Homo sapiens identified by UniProt accession Q8N7K0, 673 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N7K0; gene symbol ZNF433.
- Organism: Homo sapiens.
- Length: 673 amino acids.
- Top disease associations (Open Targets): Down syndrome, cancer and sitting height measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 433 |
|---|---|
| UniProt accession | Q8N7K0 |
| Gene | ZNF433 |
| Organism | Homo sapiens |
| Length | 673 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- Down syndrome · score 0.04
- cancer · score 0.04
- sitting height measurement · score 0.03
- neoplasm · score 0.02
- renal carcinoma · score 0.02
- nonpapillary renal cell carcinoma · score 0.02
- multiple sclerosis · score 0.01
- uterine cancer · score 0.00
- cholangiocarcinoma · score 0.00
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7K0-F1 | alphafold | PREDICTED | 74.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7K0.
Amino-acid sequence (673 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF433?
The strongest Open Targets associations for ZNF433 are Down syndrome, cancer, sitting height measurement, neoplasm and renal carcinoma.
How long is the ZNF433 protein?
The Homo sapiens ZNF433 protein (UniProt Q8N7K0) is 673 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7K0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7K0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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