Protein FAM216B (FAM216B)
Homo sapiens — UniProt Q8N7L0
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM216B (FAM216B) is a protein from Homo sapiens identified by UniProt accession Q8N7L0, 139 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q8N7L0; gene symbol FAM216B.
- Organism: Homo sapiens.
- Length: 139 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, chronic venous insufficiency and endometrial carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM216B |
|---|---|
| UniProt accession | Q8N7L0 |
| Gene | FAM216B |
| Organism | Homo sapiens |
| Length | 139 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.27
- chronic venous insufficiency · score 0.13
- endometrial carcinoma · score 0.02
- lung adenocarcinoma · score 0.01
- nasopharyngeal neoplasm · score 0.01
- lung carcinoma · score 0.01
- non-small cell lung carcinoma · score 0.01
- squamous cell carcinoma · score 0.01
- Tetralogy of Fallot · score 0.01
- ependymoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7L0-F1 | alphafold | PREDICTED | 76.77 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7L0.
Amino-acid sequence (139 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM216B?
The strongest Open Targets associations for FAM216B are alkaline phosphatase measurement, chronic venous insufficiency, endometrial carcinoma, lung adenocarcinoma and nasopharyngeal neoplasm.
How long is the FAM216B protein?
The Homo sapiens FAM216B protein (UniProt Q8N7L0) is 139 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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