Dynein light chain Tctex-type 5 (DYNLT5)
Homo sapiens — UniProt Q8N7M0
Data last refreshed: (UniProt release unknown)
Key facts
Dynein light chain Tctex-type 5 (DYNLT5) is a protein from Homo sapiens identified by UniProt accession Q8N7M0, 179 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q8N7M0; gene symbol DYNLT5.
- Organism: Homo sapiens.
- Length: 179 amino acids.
- Top disease associations (Open Targets): unipolar depression, neutrophil count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dynein light chain Tctex-type 5 |
|---|---|
| UniProt accession | Q8N7M0 |
| Gene | DYNLT5 |
| Organism | Homo sapiens |
| Length | 179 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- unipolar depression · score 0.18
- neutrophil count · score 0.18
- leukocyte count · score 0.13
- heel bone mineral density · score 0.12
- bone quantitative ultrasound measurement · score 0.12
- self reported educational attainment · score 0.09
- pulse pressure measurement · score 0.07
- heart rate · score 0.06
- ependymoma · score 0.03
- risk-taking behaviour · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7M0-F1 | alphafold | PREDICTED | 78.11 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7M0.
Amino-acid sequence (179 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DYNLT5?
The strongest Open Targets associations for DYNLT5 are unipolar depression, neutrophil count, leukocyte count, heel bone mineral density and bone quantitative ultrasound measurement.
How long is the DYNLT5 protein?
The Homo sapiens DYNLT5 protein (UniProt Q8N7M0) is 179 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7M0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7M0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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