Putative protein N-methyltransferase FAM86B1 (FAM86B1)
Homo sapiens — UniProt Q8N7N1
Data last refreshed: (UniProt release unknown)
Key facts
Putative protein N-methyltransferase FAM86B1 (FAM86B1) is a protein from Homo sapiens identified by UniProt accession Q8N7N1, 330 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q8N7N1; gene symbol FAM86B1.
- Organism: Homo sapiens.
- Length: 330 amino acids.
- Top disease associations (Open Targets): MODY, diabetes mellitus, transient neonatal, 2 and butyrylcholinesterase deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Putative protein N-methyltransferase FAM86B1 |
|---|---|
| UniProt accession | Q8N7N1 |
| Gene | FAM86B1 |
| Organism | Homo sapiens |
| Length | 330 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- MODY · score 0.08
- diabetes mellitus, transient neonatal, 2 · score 0.05
- butyrylcholinesterase deficiency · score 0.04
- hypothyroidism · score 0.03
- peak expiratory flow · score 0.03
- eosinophil percentage of leukocytes · score 0.02
- wellbeing measurement · score 0.02
- cancer · score 0.00
- bladder transitional cell carcinoma · score 0.00
- ulcerative colitis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7N1-F1 | alphafold | PREDICTED | 89.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7N1.
Amino-acid sequence (330 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM86B1?
The strongest Open Targets associations for FAM86B1 are MODY, diabetes mellitus, transient neonatal, 2, butyrylcholinesterase deficiency, hypothyroidism and peak expiratory flow.
How long is the FAM86B1 protein?
The Homo sapiens FAM86B1 protein (UniProt Q8N7N1) is 330 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7N1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7N1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.