Inactive phospholipase D5 (PLD5)
Homo sapiens — UniProt Q8N7P1
Data last refreshed: (UniProt release unknown)
Key facts
Inactive phospholipase D5 (PLD5) is a protein from Homo sapiens identified by UniProt accession Q8N7P1, 536 residues long. MolForge cross-references it against 0 known binders and 53 disease associations.
- UniProt accession: Q8N7P1; gene symbol PLD5.
- Organism: Homo sapiens.
- Length: 536 amino acids.
- Top disease associations (Open Targets): gut microbiome measurement, Myopia and age at onset.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Inactive phospholipase D5 |
|---|---|
| UniProt accession | Q8N7P1 |
| Gene | PLD5 |
| Organism | Homo sapiens |
| Length | 536 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (53)
Diseases linked to this target (Open Targets).
- gut microbiome measurement · score 0.38
- Myopia · score 0.36
- age at onset · score 0.36
- refractive error · score 0.29
- neurofibrillary tangles measurement · score 0.28
- smoking status measurement · score 0.28
- viral load · score 0.26
- PHF-tau measurement · score 0.23
- body weight · score 0.19
- metabolite measurement · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7P1-F1 | alphafold | PREDICTED | 83.10 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7P1.
Amino-acid sequence (536 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLD5?
The strongest Open Targets associations for PLD5 are gut microbiome measurement, Myopia, age at onset, refractive error and neurofibrillary tangles measurement.
How long is the PLD5 protein?
The Homo sapiens PLD5 protein (UniProt Q8N7P1) is 536 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7P1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7P1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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