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Zinc finger protein 676 (ZNF676)

Homo sapiens — UniProt Q8N7Q3

Gene: ZNF676Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Zinc finger protein 676 (ZNF676) is a protein from Homo sapiens identified by UniProt accession Q8N7Q3, 588 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

  • UniProt accession: Q8N7Q3; gene symbol ZNF676.
  • Organism: Homo sapiens.
  • Length: 588 amino acids.
  • Top disease associations (Open Targets): IGF-1 measurement, telomere length and lymphocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameZinc finger protein 676
UniProt accessionQ8N7Q3
GeneZNF676
OrganismHomo sapiens
Length588 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (33)

Diseases linked to this target (Open Targets).

  • IGF-1 measurement · score 0.33
  • telomere length · score 0.32
  • lymphocyte count · score 0.29
  • uterine fibroid · score 0.13
  • Myopia · score 0.05
  • myopia · score 0.05
  • smoking status measurement · score 0.04
  • triglyceride measurement · score 0.04
  • Shwachman-Diamond syndrome · score 0.03
  • atypical hemolytic-uremic syndrome with C3 anomaly · score 0.03

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q8N7Q3-F1alphafoldPREDICTED72.90—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7Q3.

Amino-acid sequence (588 residues)

MLENYRNLVF LGIAAFKPDL IIFLEQGKEP WNMKRHEMVE EPPVICSHFS QEFWPEQGIE DSFQKMILRR YDKCGHENLH LKISCTNVDE CNVHKEGYNK LNQSLTTTQS KVFQCGKYAN VFHKCSNSNR HKIRHTGEKG LKCKEYVRSF CMLSHLSQHE RIYTRENSYK CEENGKAFNW SSTLTYYKSI HTGEKPYKCE ECGKAFSKFS ILTKHKVIHT GEKPYKCEEC GKAFNRSSIL TKHKIIHTGE KPYKCEECGK GFSSVSTLNT HKAIHAEEKP YKCEECGKAS NSSSKLMEHK RIHTGEKPYK CEECGKAFSW SSSLTEHKRI HAGEKPYKCE ECGKAFNRSS ILTKHKIIHT GEKPYKCEGC GKAFSKVSTL NTHKAIHAEE KPYKCEECGK ASNSSSKLME HKRIHTGEKP YKCEECGKAF SWSSSLTEHK RIHAGEKPYK CEECGKAFTW SSSFTKHKRI HAAEKPYKCE ECGKGFSTFS ILTKHKIIHT GEKRYKCEEC GKAFSWSSIL TEHKIIHTGE KPYKCEECGK AFSRSSSLTR HKRIHTGEKP YKCEECGKAF KSSSTVSYHK KIHTGENP

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with ZNF676?

The strongest Open Targets associations for ZNF676 are IGF-1 measurement, telomere length, lymphocyte count, uterine fibroid and Myopia.

How long is the ZNF676 protein?

The Homo sapiens ZNF676 protein (UniProt Q8N7Q3) is 588 amino acids long.

Browse: Targets: Z · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ8N7Q3
GeneZNF676
OrganismHomo sapiens
Length588
Binders0
Diseases33
View on UniProt