POM121-like protein 12 (POM121L12)
Homo sapiens — UniProt Q8N7R1
Data last refreshed: (UniProt release unknown)
Key facts
POM121-like protein 12 (POM121L12) is a protein from Homo sapiens identified by UniProt accession Q8N7R1, 296 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q8N7R1; gene symbol POM121L12.
- Organism: Homo sapiens.
- Length: 296 amino acids.
- Top disease associations (Open Targets): smoking behavior, smoking status measurement and substance abuse.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | POM121-like protein 12 |
|---|---|
| UniProt accession | Q8N7R1 |
| Gene | POM121L12 |
| Organism | Homo sapiens |
| Length | 296 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- smoking behavior · score 0.33
- smoking status measurement · score 0.27
- substance abuse · score 0.27
- attention deficit hyperactivity disorder · score 0.27
- antisocial behaviour measurement · score 0.27
- metabolite measurement · score 0.22
- protein measurement · score 0.21
- PHF-tau measurement · score 0.17
- neurofibrillary tangles measurement · score 0.17
- age-related hearing impairment · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7R1-F1 | alphafold | PREDICTED | 52.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7R1.
Amino-acid sequence (296 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with POM121L12?
The strongest Open Targets associations for POM121L12 are smoking behavior, smoking status measurement, substance abuse, attention deficit hyperactivity disorder and antisocial behaviour measurement.
How long is the POM121L12 protein?
The Homo sapiens POM121L12 protein (UniProt Q8N7R1) is 296 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7R1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7R1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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