Cyclin-Y-like protein 1 (CCNYL1)
Homo sapiens — UniProt Q8N7R7
Data last refreshed: (UniProt release unknown)
Key facts
Cyclin-Y-like protein 1 (CCNYL1) is a protein from Homo sapiens identified by UniProt accession Q8N7R7, 359 residues long. MolForge cross-references it against 0 known binders and 114 disease associations.
- UniProt accession: Q8N7R7; gene symbol CCNYL1.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): vital capacity, systolic blood pressure and azoospermia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cyclin-Y-like protein 1 |
|---|---|
| UniProt accession | Q8N7R7 |
| Gene | CCNYL1 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (114)
Diseases linked to this target (Open Targets).
- vital capacity · score 0.27
- systolic blood pressure · score 0.17
- azoospermia · score 0.11
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- heel bone mineral density · score 0.09
- bone quantitative ultrasound measurement · score 0.08
- spermatogenic failure 72 · score 0.07
- spermatogenic failure 46 · score 0.07
- spermatogenic failure 18 · score 0.07
- spermatogenic failure 27 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7R7-F1 | alphafold | PREDICTED | 73.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7R7.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCNYL1?
The strongest Open Targets associations for CCNYL1 are vital capacity, systolic blood pressure, azoospermia, male infertility with teratozoospermia due to single gene mutation and heel bone mineral density.
How long is the CCNYL1 protein?
The Homo sapiens CCNYL1 protein (UniProt Q8N7R7) is 359 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7R7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7R7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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