BEN domain-containing protein 7 (BEND7)

About BEN domain-containing protein 7

BEN domain-containing protein 7 (BEND7) is a protein from Homo sapiens identified by UniProt accession Q8N7W2, 413 residues long. MolForge cross-references it against 0 known binders and 57 disease associations.

Target properties

Protein name	BEN domain-containing protein 7
UniProt accession	Q8N7W2
Gene	BEND7
Organism	Homo sapiens
Length	413 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (57)

Diseases linked to this target (Open Targets).

neutrophil count · score 0.46
type 2 diabetes mellitus · score 0.44
myeloid white cell count · score 0.42
leukocyte count · score 0.41
hemoglobin measurement · score 0.41
smoking status measurement · score 0.41
body fat percentage · score 0.40
diastolic blood pressure · score 0.40
hematocrit · score 0.36
basophil count · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q8N7W2-F1	alphafold	PREDICTED	61.95	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7W2.

Amino-acid sequence (413 residues)

MEFSERKRSR KSQSFKLVSR DYHHEVYKIP EFSNDVNGEA KETQPIFLGD ESMEIKKQIT GMRRLLNDST GRIYQRVGKE GEKLKEEPQD LDLVWPPRLN SSAEAPQSLH PSSRGVWNEL PPQSGQFSGQ YGTRSRTFQS QPHPTTSSNG ELPVVNSSAG SNCCTCNCQS TLQAILQELK TMRKLMQIQA VGTQNRQQPP ISLICSQRTA VSRKRNKKKK VPPKTVEPLT VKQKPSGSEM EKKSVVASEL SALQAAEHTS PEESRVLGFG IVLESPSSDP EVQLAEGFDV FMPKSQLDSI LSNYTRSGSL LFRKLVCAFF DDKTLANSLP NGKRKRGLND NRKGLDQNIV GAIKVFTEKY CTANHVDKLP GPRDWVQILQ DQIKLARRRL KRGSEIADSD ERLDGIALPP TVV

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards