Androglobin (ADGB)
Homo sapiens — UniProt Q8N7X0
Data last refreshed: (UniProt release unknown)
Key facts
Androglobin (ADGB) is a protein from Homo sapiens identified by UniProt accession Q8N7X0, 1667 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.
- UniProt accession: Q8N7X0; gene symbol ADGB.
- Organism: Homo sapiens.
- Length: 1667 amino acids.
- Top disease associations (Open Targets): protein measurement, leprosy and fragile X syndrome.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Androglobin |
|---|---|
| UniProt accession | Q8N7X0 |
| Gene | ADGB |
| Organism | Homo sapiens |
| Length | 1667 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (117)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.42
- leprosy · score 0.36
- fragile X syndrome · score 0.33
- gut microbiome measurement · score 0.28
- neurodegenerative disease · score 0.18
- metabolite measurement · score 0.13
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- partial chromosome Y deletion · score 0.08
- congenital bilateral absence of vas deferens · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7X0-F1 | alphafold | PREDICTED | 66.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7X0.
Amino-acid sequence (1667 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ADGB?
The strongest Open Targets associations for ADGB are protein measurement, leprosy, fragile X syndrome, gut microbiome measurement and neurodegenerative disease.
How long is the ADGB protein?
The Homo sapiens ADGB protein (UniProt Q8N7X0) is 1667 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7X0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7X0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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