Melanoma-associated antigen B6 (MAGEB6)
Homo sapiens — UniProt Q8N7X4
Data last refreshed: (UniProt release unknown)
Key facts
Melanoma-associated antigen B6 (MAGEB6) is a protein from Homo sapiens identified by UniProt accession Q8N7X4, 407 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q8N7X4; gene symbol MAGEB6.
- Organism: Homo sapiens.
- Length: 407 amino acids.
- Top disease associations (Open Targets): hepatocellular carcinoma, neoplasm and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Melanoma-associated antigen B6 |
|---|---|
| UniProt accession | Q8N7X4 |
| Gene | MAGEB6 |
| Organism | Homo sapiens |
| Length | 407 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- hepatocellular carcinoma · score 0.01
- neoplasm · score 0.01
- head and neck squamous cell carcinoma · score 0.01
- Azoospermia · score 0.01
- azoospermia · score 0.01
- cancer · score 0.00
- calf circumference measurement · score 0.00
- sarcoma · score 0.00
- diabetes mellitus · score 0.00
- melanoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q8N7X4-F1 | alphafold | PREDICTED | 69.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q8N7X4.
Amino-acid sequence (407 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAGEB6?
The strongest Open Targets associations for MAGEB6 are hepatocellular carcinoma, neoplasm, head and neck squamous cell carcinoma, Azoospermia and azoospermia.
How long is the MAGEB6 protein?
The Homo sapiens MAGEB6 protein (UniProt Q8N7X4) is 407 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q8N7X4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q8N7X4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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